Betameson Ointment Ointment – (0.05%)

Square Pharmaceuticals PLC.

Generic: Betamethasone valerate 0.05% Topical

Weight

0.015 kg

0 People watching this product now!

Indication

Eczema, atopic dermatitis, contact dermatitis, systemic lupus erythematosus, lichen planus, lichen simplex, psoriasis, prurigo nodularis, plaque psoriasis

Administration

Topical Administration Use medium to very high potency for less than 2 weeks to reduce local and systemic side effects Use low potency for chronic therapy Avoid medium to very high potency on face, folds, and groin, because use in these areas can increase steroid absorption Use lower potency for children (ie, increased BSA/kg, therefore increased systemic absorption)

Adult Dose

As valerate: Apply sparingly 2-3 times daily. Cream for moist & ointment for dry surface.

Contraindication

Underlying infection, Hypersensitivity, Ophthalmic use

Mode of Action

Betamethasone is a corticosteroid with mainly glucocorticoid activity. It prevents and controls inflammation by controlling the rate of protein synthesis, depressing the migration of polymorphonuclear leukocytes and fibroblasts, and reversing capillary permeability and lysosomal stabilisation.

Precaution

Chronic topical corticosteroid therapy may interfere with growth and development in children. Lactation: It is not known whether topical corticosteroid use could result in sufficient systemic absorption to produce detectable quantities in human milk; use with caution.

Side Effect

Dermal atrophy, local irritation, folliculitis, hypertrichosis, burning, dry skin, pigmentation changes, HPA suppression (with higher potency used >2 wk)

Pregnancy Category Note

Pregnancy There are no available data on ointment use in pregnant women to identify a drug- associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes; observational studies suggest an increased risk of low birth weight infants with the use of greater than 300 grams of potent or very potent topical corticosteroid during a pregnancy; advise pregnant women that the ointment may increase risk of having a low birth weight infant and to use it on the smallest area of skin and for the shortest duration possible Animal data In animal reproduction studies, increased malformations, including umbilical…

-10%